WHAT IS PURE RETINOL? There are many retinols available in the market: complexes, derivatives, and PURE. Dermatologists recommend Pure Retinol because it is the most researched and effective anti-aging ingredient. With many retinols available in skincare, always look for those that say PURE. 0.3% Pure Retinol is an optimal concentration that has been dermatologist-validated for fast, visible results.