Primin

Primin is a naturally occurring chemical found in the primrose flowering house plant (Primula obconica). The chemical is also used as a botanical extract added to skin care products and medications.

Allergic contact dermatitis to primin can be prevented by avoiding most specimens of Primula obconica. Touching or handling the plant can affect fingers, hands, and other exposed skin such as arms, neck, and face. The leaves of Primula obconica, which are round and covered with fine hair-like appendages called trichomes, are the usual cause of skin irritation. Primin is a powerful sensitizing substance contained in the fine hairs, and the content varies with the season, hours of sunshine and care of the plant. A hybrid version of the plant called Libre is primin-free and eliminates allergy to Primula obconica. Other types of primrose plants do not contain primin and thus can be handled without a problem.